Bronchial hyperresponsiveness and cytokines in virus-induced asthma exacerbations
نویسندگان
چکیده
منابع مشابه
Bronchial Hyperresponsiveness in Asthma*
Measurement ofnonspecific bronchial hyperresponsiveness remains largely a research tool in asthma, and its usefulness in the assessment and management of asthma is poorly defined. We StUdied the relationship of bronchial hyperresponsiveness to the clinical severity of asthma in 54 asthmatic subjects. In order to find out whether measurement of bronchial hyperresponsiveness could be used to pred...
متن کاملVirus-induced exacerbations in asthma and COPD
Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway inflammation and/or airflow limitation due to pulmonary emphysema. Chronic bronchitis, pulmonary emphysema, and bronchial asthma may all be associated with airflow limitation; therefore, exacerbation of asthma may be associated with the pathophysiology of COPD. Furthermore, recent studies have suggested that the exa...
متن کاملDetecting asthma and bronchial hyperresponsiveness in children.
The prevalence of asthma in children is increasing worldwide. Although the features of asthma are well documented, defining asthma remains a problem. The clinical definition of asthma does not take into account the concept of airway inflammation. A broader definition that incorporates the inflammatory process, reversibility of airway obstruction, and airway responsiveness needs to be more widel...
متن کاملAllergen-induced Bronchial Hyperresponsiveness
Bradykinin (BK) is a peptide mediator generated at sites of inflammation and its effects are mediated through constitutively expressed B 2 receptor or through induction of B 1 receptors. We examined the role of these receptors in bronchial hyperresponsiveness (BHR). Brown-Norway rats sensitized with ovalbumin (OA) and Al(OH) 3 intraperitoneally, were exposed 3 wk later to either saline or OA ae...
متن کاملVirus Infection-Induced Bronchial Asthma Exacerbation
Infection with respiratory viruses, including rhinoviruses, influenza virus, and respiratory syncytial virus, exacerbates asthma, which is associated with processes such as airway inflammation, airway hyperresponsiveness, and mucus hypersecretion. In patients with viral infections and with infection-induced asthma exacerbation, inflammatory mediators and substances, including interleukins (ILs)...
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ژورنال
عنوان ژورنال: Clinical <html_ent glyph="@amp;" ascii="&"/> Experimental Allergy
سال: 1997
ISSN: 0954-7894,1365-2222
DOI: 10.1046/j.1365-2222.1997.d01-429.x